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Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease
- Deborah A. Roby,
- Fernanda Ruiz,
- Bailey A. Kermath,
- Jaymie R. Voorhees,
- Michael Niehoff,
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Jinsong Zhang,
Roles Formal analysis
Affiliation Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, MO, United States of America
⨯ - John E. Morley,
- Erik S. Musiek,
- Susan A. Farr ,
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Thomas P. Burris
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: burristhomas@wustl.edu (TPB); Susan.farr@health.slu.edu (SAF)
Affiliation Center for Clinical Pharmacology, Washington University School of Medicine and St. Louis College of Pharmacy, St. Louis, MO, United States of America
⨯
http://orcid.org/0000-0002-8798-7316
Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease
- Deborah A. Roby,
- Fernanda Ruiz,
- Bailey A. Kermath,
- Jaymie R. Voorhees,
- Michael Niehoff,
- Jinsong Zhang,
- John E. Morley,
- Erik S. Musiek,
- Susan A. Farr,
- Thomas P. Burris
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- Published: April 11, 2019
- https://doi.org/10.1371/journal.pone.0215004