Data analysis algorithm for the development of extracellular miRNA-based diagnostic systems for prostate cancer

O. E. Bryzgunova; I. A. Zaporozhchenko; E. A. Lekchnov; E. V. Amelina; M. Yu. Konoshenko; S. V. Yarmoschuk; O. A. Pashkovskaya; A. A. Zheravin; S. V. Pak; E. Yu. Rykova; P. P. Laktionov

doi:10.1371/journal.pone.0215003

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Open Access

Peer-reviewed

Research Article

Data analysis algorithm for the development of extracellular miRNA-based diagnostic systems for prostate cancer

O. E. Bryzgunova,

Roles Conceptualization, Data curation, Investigation, Validation, Visualization, Writing – original draft

Affiliations The Laboratory of Molecular Medicine, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia, The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯
I. A. Zaporozhchenko ,

Roles Formal analysis, Validation, Writing – review & editing

* E-mail: msol@ngs.ru

Affiliations The Laboratory of Molecular Medicine, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia, The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia

http://orcid.org/0000-0001-9101-2207

⨯
E. A. Lekchnov,

Roles Investigation, Validation

Affiliations The Laboratory of Molecular Medicine, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia, The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯
E. V. Amelina,

Roles Formal analysis

Affiliation Federal State Autonomous Educational Institution of Higher Education "Novosibirsk National Research University", Novosibirsk, Russia
⨯
M. Yu. Konoshenko,

Roles Writing – review & editing

Affiliations The Laboratory of Molecular Medicine, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia, The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia

http://orcid.org/0000-0003-2925-9350

⨯
S. V. Yarmoschuk,

Roles Resources

Affiliation The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯
O. A. Pashkovskaya,

Roles Resources

Affiliation The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯
A. A. Zheravin,

Roles Resources

Affiliation The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯
S. V. Pak,

Roles Resources

Affiliation The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯
E. Yu. Rykova,

Roles Project administration

Affiliations The Laboratory of Molecular Medicine, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia, The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia, Novosibirsk State Technical University, Novosibirsk, Russia
⨯
P. P. Laktionov

Roles Conceptualization, Supervision, Writing – review & editing

Affiliations The Laboratory of Molecular Medicine, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia, The Laboratory of Biomedical Technologies, Centre of New Medical Technologies,“E. Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, Novosibirsk, Russia
⨯

Data analysis algorithm for the development of extracellular miRNA-based diagnostic systems for prostate cancer

O. E. Bryzgunova,
I. A. Zaporozhchenko,
E. A. Lekchnov,
E. V. Amelina,
M. Yu. Konoshenko,
S. V. Yarmoschuk,
O. A. Pashkovskaya,
A. A. Zheravin,
S. V. Pak,
E. Yu. Rykova

Published: April 10, 2019
https://doi.org/10.1371/journal.pone.0215003

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MicroRNAs
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