Survival of Mycobacterium bovis BCG oral vaccine during transit through a dynamic in vitro model simulating the upper gastrointestinal tract of badgers

Gareth A. Williams; Marjorie E. Koenen; Robert Havenaar; Paul Wheeler; Sonya Gowtage; Sandrine Lesellier; Mark A. Chambers

doi:10.1371/journal.pone.0214859

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Open Access

Peer-reviewed

Research Article

Survival of Mycobacterium bovis BCG oral vaccine during transit through a dynamic in vitro model simulating the upper gastrointestinal tract of badgers

Gareth A. Williams,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Department of Bacteriology, Animal and Plant Health Agency, New Haw, Addlestone, United Kingdom
⨯
Marjorie E. Koenen,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

Current address: Triskelion B.V., Zeist, The Netherlands.

Affiliation Earth, Environmental and Life Sciences, Netherlands Organization for Applied Scientific Research (TNO), Zeist, The Netherlands
⨯
Robert Havenaar,

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – review & editing

Current address: Triskelion B.V., Zeist, The Netherlands.

Affiliation Earth, Environmental and Life Sciences, Netherlands Organization for Applied Scientific Research (TNO), Zeist, The Netherlands
⨯
Paul Wheeler,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Department of Bacteriology, Animal and Plant Health Agency, New Haw, Addlestone, United Kingdom
⨯
Sonya Gowtage,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Department of Bacteriology, Animal and Plant Health Agency, New Haw, Addlestone, United Kingdom
⨯
Sandrine Lesellier,

Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Department of Bacteriology, Animal and Plant Health Agency, New Haw, Addlestone, United Kingdom
⨯
Mark A. Chambers

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

* E-mail: mark.chambers@apha.gov.uk

Affiliations Department of Bacteriology, Animal and Plant Health Agency, New Haw, Addlestone, United Kingdom, Department of Pathology and Infectious Diseases, School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom

http://orcid.org/0000-0002-8073-8069

⨯

Survival of Mycobacterium bovis BCG oral vaccine during transit through a dynamic in vitro model simulating the upper gastrointestinal tract of badgers

Gareth A. Williams,
Marjorie E. Koenen,
Robert Havenaar,
Paul Wheeler,
Sonya Gowtage,
Sandrine Lesellier,
Mark A. Chambers

Published: April 19, 2019
https://doi.org/10.1371/journal.pone.0214859

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Badgers
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