Novel liquid-liquid extraction and self-emulsion methods for simplified isolation of extra-virgin olive oil phenolics with emphasis on (-)-oleocanthal and its oral anti-breast cancer activity

• Abu Bakar Siddique,

  Roles Investigation, Methodology, Validation, Writing – original draft

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  http://orcid.org/0000-0001-5424-9475

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• Hassan Ebrahim,

  Roles Methodology

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

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• Mohamed Mohyeldin,

  Roles Methodology

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  http://orcid.org/0000-0001-9052-7620

  ⨯
• Mohammed Qusa,

  Roles Methodology

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  ⨯
• Yazan Batarseh,

  Roles Methodology

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  ⨯
• Ahmed Fayyad,

  Roles Methodology

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  ⨯
• Afsana Tajmim,

  Roles Methodology

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  http://orcid.org/0000-0003-4717-1141

  ⨯
• Sami Nazzal,

  Roles Investigation, Supervision

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  ⨯
• Amal Kaddoumi,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliation Department of Drug Discovery & Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama, United States of America

  http://orcid.org/0000-0001-9792-7766

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• Khalid El Sayed

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: elsayed@ulm.edu

  Affiliation School of Basic Pharmaceutical & Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, United States of America

  http://orcid.org/0000-0002-1456-4064

  ⨯