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Open Access
Peer-reviewed
Research Article
In-utero epigenetic factors are associated with early-onset myopia in young children
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Wei Jie Seow ,
Contributed equally to this work with: Wei Jie Seow, Cheryl S. Ngo
Roles Writing – original draft, Writing – review & editing
Affiliations Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore
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Cheryl S. Ngo ,
Contributed equally to this work with: Wei Jie Seow, Cheryl S. Ngo
Roles Writing – original draft, Writing – review & editing
Affiliation Department of Ophthalmology, National University Health System, Singapore
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Hong Pan,
Roles Data curation, Formal analysis
Affiliation Singapore Institute for Clinical Sciences (SICS), A*STAR, Brenner Centre for Molecular Medicine, Singapore
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Veluchamy Amutha Barathi,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliations Singapore Eye Research Institute, Singapore, The Ophthalmology and Visual Sciences Academic Clinical Program, DUKE-NUS Graduate Medical School, Singapore, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Stuart W. Tompson,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, Madison, Wisconsin, United States of America
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Kristina N. Whisenhunt,
Roles Writing – review & editing
Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, Madison, Wisconsin, United States of America
⨯ - Eranga Vithana,
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Yap-Seng Chong,
Roles Conceptualization, Funding acquisition, Writing – review & editing
Affiliation Department of Obstetrics and Gynaecology, National University of Singapore, Singapore, Singapore
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Suh-Hang H. Juo,
Roles Formal analysis, Writing – review & editing
Affiliation Institute of New Drug Development, Center for Myopia and Eye diseases, China Medical University and China Medical University Hospital, Taichung, Taiwan
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Pirro Hysi,
Roles Writing – review & editing
Affiliations Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom, Johns Hopkins School of Public Health, Baltimore, Maryland, United States
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Terri L. Young,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, Madison, Wisconsin, United States of America
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Neerja Karnani,
Roles Data curation, Methodology, Writing – review & editing
Affiliation Singapore Institute for Clinical Sciences (SICS), A*STAR, Brenner Centre for Molecular Medicine, Singapore
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Seang Mei Saw
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: ephssm@nus.edu.sg
Affiliations Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore Eye Research Institute, Singapore, The Ophthalmology and Visual Sciences Academic Clinical Program, DUKE-NUS Graduate Medical School, Singapore
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In-utero epigenetic factors are associated with early-onset myopia in young children
- Wei Jie Seow,
- Cheryl S. Ngo,
- Hong Pan,
- Veluchamy Amutha Barathi,
- Stuart W. Tompson,
- Kristina N. Whisenhunt,
- Eranga Vithana,
- Yap-Seng Chong,
- Suh-Hang H. Juo,
- Pirro Hysi
- Published: May 17, 2019
- https://doi.org/10.1371/journal.pone.0214791