Pharmacological and molecular dynamics analyses of differences in inhibitor binding to human and nematode PDE4: Implications for management of parasitic nematodes

• Kevin D. Schuster ,

  Contributed equally to this work with: Kevin D. Schuster, Mohammadjavad Mohammadi

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States of America

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• Mohammadjavad Mohammadi ,

  Contributed equally to this work with: Kevin D. Schuster, Mohammadjavad Mohammadi

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Chemical Engineering, University of New Hampshire, Durham, NH, United States of America

  http://orcid.org/0000-0001-7344-0857

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• Karyn B. Cahill,

  Roles Data curation, Investigation, Methodology, Supervision

  Current address: Envirologix Incorporated, Portland, ME, United States of America.

  Affiliation Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States of America

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• Suzanne L. Matte,

  Roles Investigation, Methodology

  Affiliation Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States of America

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• Alexis D. Maillet,

  Roles Investigation

  Affiliation Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States of America

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• Harish Vashisth ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: rick.cote@unh.edu (RHC); harish.vashisth@unh.edu (HV)

  Affiliation Department of Chemical Engineering, University of New Hampshire, Durham, NH, United States of America

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• Rick H. Cote

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: rick.cote@unh.edu (RHC); harish.vashisth@unh.edu (HV)

  Affiliation Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States of America

  http://orcid.org/0000-0002-1573-6526

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