CD46 knock-out using CRISPR/Cas9 editing of hTERT immortalized human cells modulates complement activation

• Matthias Wieser,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Evercyte GmbH, Vienna, Austria

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• Teresa Francisci,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Evercyte GmbH, Vienna, Austria

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• Daniel Lackner,

  Roles Conceptualization, Data curation, Investigation, Supervision

  Affiliation Horizon Genomics GmbH, Vienna, Austria

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• Tilmann Buerckstuemmer,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Horizon Genomics GmbH, Vienna, Austria

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• Kamilla Wasner,

  Roles Data curation, Formal analysis, Methodology, Visualization

  Affiliation Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria

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• Wolf Eilenberg,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Surgery, Medical University of Vienna, Vienna, Austria

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• Anton Stift,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Surgery, Medical University of Vienna, Vienna, Austria

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• Markus Wahrmann,

  Roles Conceptualization, Data curation, Investigation, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria

  http://orcid.org/0000-0002-1301-8694

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• Georg A. Böhmig,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria

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• Johannes Grillari,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Evercyte GmbH, Vienna, Austria, Department of Biotechnology, BOKU Vienna, Vienna, Austria, Austrian Cluster for Tissue Regeneration, Vienna, Austria, Christian Doppler Laboratory for Biotechnology of Skin Aging, Vienna, Austria

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• Regina Grillari-Voglauer

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Supervision, Writing – review & editing

  * E-mail: regina.grillari@evercyte.com

  Affiliations Evercyte GmbH, Vienna, Austria, Department of Biotechnology, BOKU Vienna, Vienna, Austria, Austrian Cluster for Tissue Regeneration, Vienna, Austria

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