Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com

Martyna Nowacka; Humberto Fernandes; Agnieszka Kiliszek; Agata Bernat; Grzegorz Lach; Janusz M. Bujnicki

doi:10.1371/journal.pone.0214481

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Open Access

Peer-reviewed

Research Article

Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com

Martyna Nowacka ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: mnowacka@genesilico.pl; iamb@genesilico.pl(JMB)

Current address: Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Warsaw, Poland

Affiliation International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland

http://orcid.org/0000-0001-7682-6384

⨯
Humberto Fernandes,

Roles Data curation, Formal analysis, Validation, Visualization, Writing – review & editing

Affiliation Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
⨯
Agnieszka Kiliszek,

Roles Data curation, Formal analysis, Validation, Writing – review & editing

Affiliation Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
⨯
Agata Bernat,

Roles Investigation, Methodology, Writing – review & editing

Affiliation International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland
⨯
Grzegorz Lach,

Roles Methodology, Software, Writing – review & editing

Current address: Institute of Theoretical Physics, Faculty of Physics, University of Warsaw, Warsaw, Poland

Affiliation International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland
⨯
Janusz M. Bujnicki

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Validation, Writing – review & editing

* E-mail: mnowacka@genesilico.pl; iamb@genesilico.pl(JMB)

Affiliations International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland
⨯

Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com

Martyna Nowacka,
Humberto Fernandes,
Agnieszka Kiliszek,
Agata Bernat,
Grzegorz Lach,
Janusz M. Bujnicki

Published: April 25, 2019
https://doi.org/10.1371/journal.pone.0214481

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RNA structure
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RNA stem-loop structure
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Sequence motif analysis
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RNA-binding proteins
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Crystal structure
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Hydrogen bonding
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Double stranded RNA
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Electrophoretic mobility shift assay
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