A new technology for increasing therapeutic protein levels in the brain over extended periods

• Ryosuke Nakano,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – original draft, Writing – review & editing

  Affiliations Research and Development Division, Kyowa Hakko Kirin Co., LTD., Machida-shi, Tokyo, Japan, Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University, Kagoshima, Japan

  ⨯
• Sayaka Takagi-Maeda,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Research and Development Division, Kyowa Hakko Kirin Co., LTD., Machida-shi, Tokyo, Japan

  ⨯
• Yuji Ito,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University, Kagoshima, Japan

  ⨯
• Satoshi Kishimoto,

  Roles Data curation, Funding acquisition, Investigation, Methodology

  Affiliation Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University, Kagoshima, Japan

  ⨯
• Tomoko Osato,

  Roles Funding acquisition, Methodology

  Affiliation Research and Development Division, Kyowa Hakko Kirin Co., LTD., Machida-shi, Tokyo, Japan

  ⨯
• Kaori Noguchi,

  Roles Funding acquisition, Methodology

  Affiliation Research and Development Division, Kyowa Hakko Kirin Co., LTD., Machida-shi, Tokyo, Japan

  ⨯
• Kana Kurihara-Suda,

  Roles Funding acquisition, Methodology

  Affiliation Research and Development Division, Kyowa Hakko Kirin Co., LTD., Machida-shi, Tokyo, Japan

  ⨯
• Nobuaki Takahashi

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: nobuaki.takahashi@kyowa-kirin.co.jp

  Affiliation Research and Development Division, Kyowa Hakko Kirin Co., LTD., Chiyoda-ku, Tokyo, Japan

  http://orcid.org/0000-0002-0047-6725

  ⨯