Hypoxia and mesenchymal stromal cells as key drivers of initial fracture healing in an equine in vitro fracture hematoma model

• Moritz Pfeiffenberger ,

  Contributed equally to this work with: Moritz Pfeiffenberger, Janika Bartsch

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliations Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany, German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany

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• Janika Bartsch ,

  Contributed equally to this work with: Moritz Pfeiffenberger, Janika Bartsch

  Roles Data curation, Investigation, Methodology, Writing – original draft

  Affiliation Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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• Paula Hoff,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliations Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany, German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany

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• Igor Ponomarev,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Research Center of Medical Technology and Biotechnology, Bad Langensalza, Germany

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• Dirk Barnewitz,

  Roles Resources, Writing – review & editing

  Affiliation Research Center of Medical Technology and Biotechnology, Bad Langensalza, Germany

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• Christa Thöne-Reineke,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliation Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany

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• Frank Buttgereit,

  Roles Formal analysis, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany, German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany

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• Timo Gaber ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany, German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany

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• Annemarie Lang

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft

  * E-mail: annemarie.lang@charite.de

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany, German Rheumatism Research Centre (DRFZ) Berlin, a Leibniz Institute, Berlin, Germany

  http://orcid.org/0000-0002-6539-9476

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