Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (T_H1)/T_H17 responses and autoimmunity

• Sung-Uk Lee,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Neurology, University of California, Irvine, Irvine, California, United States of America, Glixis Therapeutics, LLC, Santa Rosa, California, United States of America

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• Carey F. Li,

  Roles Data curation, Investigation

  Affiliation Department of Neurology, University of California, Irvine, Irvine, California, United States of America

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• Christie-Lynn Mortales,

  Roles Data curation, Investigation

  Affiliation Department of Microbiology & Molecular Genetics, University of California, Irvine, Irvine, California, United States of America

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• Judy Pawling,

  Roles Data curation, Investigation

  Affiliation Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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• James W. Dennis,

  Roles Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliations Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

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• Ani Grigorian,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Glixis Therapeutics, LLC, Santa Rosa, California, United States of America

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• Michael Demetriou

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mdemetri@uci.edu

  Affiliations Department of Neurology, University of California, Irvine, Irvine, California, United States of America, Department of Microbiology & Molecular Genetics, University of California, Irvine, Irvine, California, United States of America, Institute for Immunology, University of California, Irvine, Irvine, California, United States of America

  http://orcid.org/0000-0001-8547-5774

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