Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

• Amanda H. Kahn-Kirby ,

  Roles Conceptualization, Formal analysis, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: AKahn-Kirby@BioElectron.com

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

  http://orcid.org/0000-0002-8878-0413

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• Akiko Amagata ,

  Contributed equally to this work with: Akiko Amagata, Celine I. Maeder

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Celine I. Maeder ,

  Contributed equally to this work with: Akiko Amagata, Celine I. Maeder

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Janet J. Mei,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Steve Sideris,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Yuko Kosaka,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Andrew Hinman,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Stephanie A. Malone,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Joel J. Bruegger,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Leslie Wang,

  Roles Data curation, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

  ⨯
• Virna Kim,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• William D. Shrader,

  Roles Conceptualization, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

  ⨯
• Kevin G. Hoff,

  Roles Data curation, Supervision, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

  ⨯
• Joey C. Latham,

  Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

  ⨯
• Euan A. Ashley,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Stanford Center for Undiagnosed Diseases, Stanford University School of Medicine, Stanford, California, United States of America

  ⨯
• Matthew T. Wheeler,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Stanford Center for Undiagnosed Diseases, Stanford University School of Medicine, Stanford, California, United States of America

  ⨯
• Enrico Bertini,

  Roles Conceptualization, Writing – review & editing

  Affiliation Unit of Neuromuscular and Neurodegenerative Disorders, Bambino Gesù Children’s Research Hospital, Rome, Italy

  ⨯
• Rosalba Carrozzo,

  Roles Conceptualization, Writing – review & editing

  Affiliation Unit of Neuromuscular and Neurodegenerative Disorders, Bambino Gesù Children’s Research Hospital, Rome, Italy

  ⨯
• Diego Martinelli,

  Roles Conceptualization, Writing – review & editing

  Affiliation Unit of Neuromuscular and Neurodegenerative Disorders, Bambino Gesù Children’s Research Hospital, Rome, Italy

  ⨯
• Carlo Dionisi-Vici,

  Roles Conceptualization, Writing – review & editing

  Affiliation Clinical Division and Research Unit of Metabolic Diseases, Bambino Gesù Children's Hospital, Rome, Italy

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• Kimberly A. Chapman,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Children’s National Rare Disease Institute, Children's National Health System, Washington, D.C., United States of America

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• Gregory M. Enns,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Medical Genetics, Stanford University School of Medicine, Stanford, California, United States of America

  ⨯
• William Gahl,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation NIH Undiagnosed Diseases Program, National Human Genome Research Institute (NHGRI), National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Lynne Wolfe,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation NIH Undiagnosed Diseases Program, National Human Genome Research Institute (NHGRI), National Institutes of Health, Bethesda, Maryland, United States of America

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• Russell P. Saneto,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Division of Pediatric Neurology, Department of Neurology, Neuroscience Institute, Seattle Children's Hospital, Seattle, Washington, United States of America

  ⨯
• Simon C. Johnson,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliations Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America, Department of Neurology, University of Washington, Seattle, Washington, United States of America

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• Jeffrey K. Trimmer,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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• Matthew B. Klein,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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•  [ ... ],
• Charles R. Holst

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation BioElectron Technology Corporation, Mountain View, California, United States of America

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