Reduction of CFU-GM and circulating hematopoietic progenitors in a subgroup of children with chronic neutropenia associated with severe infections and delayed recovery

Fabio Timeus; Nicoletta Crescenzio; Luiselda Foglia; Alessandra Doria; Maria Giuseppina Stillitano; Emanuela Garelli; Raffaela Mazzone; Laura Vivalda; Stefano Vallero; Ugo Ramenghi; Paola Saracco

doi:10.1371/journal.pone.0213782

Loading metrics

Open Access

Peer-reviewed

Research Article

Reduction of CFU-GM and circulating hematopoietic progenitors in a subgroup of children with chronic neutropenia associated with severe infections and delayed recovery

Fabio Timeus ,

Roles Conceptualization, Project administration, Supervision, Visualization, Writing – original draft

* E-mail: fabio.timeus@unito.it

Affiliation Pediatric Onco-Hematology, Regina Margherita Children Hospital, Turin, Italy

http://orcid.org/0000-0003-0095-283X

⨯
Nicoletta Crescenzio,

Roles Investigation, Project administration, Validation

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Luiselda Foglia,

Roles Investigation

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Alessandra Doria,

Roles Investigation

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Maria Giuseppina Stillitano,

Roles Investigation

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Emanuela Garelli,

Roles Investigation

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Raffaela Mazzone,

Roles Investigation

Affiliation Biochemistry Laboratory, Regina Margherita Children Hospital, Turin, Italy
⨯
Laura Vivalda,

Roles Data curation

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Stefano Vallero,

Roles Formal analysis

Affiliation Pediatric Onco-Hematology, Regina Margherita Children Hospital, Turin, Italy
⨯
Ugo Ramenghi,

Roles Resources, Supervision, Writing – review & editing

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯
Paola Saracco

Roles Conceptualization, Supervision, Visualization, Writing – review & editing

Affiliation Pediatric Hematology, Regina Margherita Children Hospital, University of Turin, Turin, Italy
⨯

Reduction of CFU-GM and circulating hematopoietic progenitors in a subgroup of children with chronic neutropenia associated with severe infections and delayed recovery

Fabio Timeus,
Nicoletta Crescenzio,
Luiselda Foglia,
Alessandra Doria,
Maria Giuseppina Stillitano,
Emanuela Garelli,
Raffaela Mazzone,
Laura Vivalda,
Stefano Vallero,
Ugo Ramenghi

Published: March 14, 2019
https://doi.org/10.1371/journal.pone.0213782

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Neutropenia
Is the Subject Area "Neutropenia" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Cell enumeration techniques
Is the Subject Area "Cell enumeration techniques" applicable to this article?

Thanks for your feedback.
Pediatric infections
Is the Subject Area "Pediatric infections" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Pediatrics
Is the Subject Area "Pediatrics" applicable to this article?

Thanks for your feedback.