TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer

Geun Taek Lee; Jeffrey A. Rosenfeld; Won Tae Kim; Young Suk Kwon; Ganesh Palapattu; Rohit Mehra; Wun-Jae Kim; Isaac Yi Kim

doi:10.1371/journal.pone.0213488

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Open Access

Peer-reviewed

Research Article

TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer

Geun Taek Lee,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliation Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, and Division of Urology, Rutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States of America
⨯
Jeffrey A. Rosenfeld,

Roles Investigation

Affiliation Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, and Division of Urology, Rutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States of America
⨯
Won Tae Kim,

Roles Formal analysis

Affiliations Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, and Division of Urology, Rutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States of America, Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea
⨯
Young Suk Kwon,

Roles Investigation

Affiliation Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, and Division of Urology, Rutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States of America
⨯
Ganesh Palapattu,

Roles Resources

Affiliation Department of Urology, University of Michigan, Ann Arbor, MI, United States of America
⨯
Rohit Mehra,

Roles Resources

Affiliation Department of Urology, University of Michigan, Ann Arbor, MI, United States of America
⨯
Wun-Jae Kim,

Roles Supervision

Affiliation Department of Urology, Chungbuk National University College of Medicine, Cheongju, Korea
⨯
Isaac Yi Kim

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: kimiy@cinj.rutgers.edu

Affiliation Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, and Division of Urology, Rutgers Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, NJ, United States of America
⨯

TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer

Geun Taek Lee,
Jeffrey A. Rosenfeld,
Won Tae Kim,
Young Suk Kwon,
Ganesh Palapattu,
Rohit Mehra,
Wun-Jae Kim,
Isaac Yi Kim

Published: September 19, 2019
https://doi.org/10.1371/journal.pone.0213488
See the preprint

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