miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells

Masahiro Yoshida; Hiroto Horiguchi; Shohei Kikuchi; Satoshi Iyama; Hiroshi Ikeda; Akari Goto; Yutaka Kawano; Kazuyuki Murase; Kohichi Takada; Koji Miyanishi; Junji Kato; Masayoshi Kobune

doi:10.1371/journal.pone.0213220

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Open Access

Peer-reviewed

Research Article

miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells

Masahiro Yoshida,

Roles Data curation, Investigation

Affiliations Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan, Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Hiroto Horiguchi,

Roles Investigation

Affiliation Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Shohei Kikuchi,

Roles Formal analysis, Investigation

Affiliations Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan, Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Satoshi Iyama,

Roles Investigation

Affiliation Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Hiroshi Ikeda,

Roles Investigation

Affiliation Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Akari Goto,

Roles Investigation

Affiliation Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Yutaka Kawano,

Roles Investigation, Visualization

Affiliation Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Kazuyuki Murase,

Roles Investigation

Affiliations Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan, Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Kohichi Takada,

Roles Investigation

Affiliations Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan, Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Koji Miyanishi,

Roles Formal analysis, Investigation

Affiliation Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Junji Kato,

Roles Writing – review & editing

Affiliation Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
⨯
Masayoshi Kobune

Roles Funding acquisition, Methodology, Writing – original draft

* E-mail: mkobune@sapmed.ac.jp

Affiliation Department of Hematology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan

http://orcid.org/0000-0003-3828-8444

⨯

miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells

Masahiro Yoshida,
Hiroto Horiguchi,
Shohei Kikuchi,
Satoshi Iyama,
Hiroshi Ikeda,
Akari Goto,
Yutaka Kawano,
Kazuyuki Murase,
Kohichi Takada,
Koji Miyanishi

Published: March 5, 2019
https://doi.org/10.1371/journal.pone.0213220

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Mesenchymal stem cells
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MicroRNAs
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Gene expression
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Acute myeloid leukemia
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Cell cycle and cell division
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Signal inhibition
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