Effect of cyclical intermittent hypoxia on Ad5CMVCre induced solitary lung cancer progression and spontaneous metastases in the Kras^G12D+; p53^fl/fl; myristolated p110^fl/fl ROSA-gfp mouse

• Xiaofeng Guo ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ These authors are co-first authors on this work.

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Yan Liu ,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  ¶‡ These authors are co-first authors on this work.

  Affiliation Department of Otolaryngology Head and Neck Surgery, the Second Hospital, Jilin University, Changchun, Jilin Province, China

  ⨯
• Jessica L. Kim,

  Roles Data curation, Investigation

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Emily Y. Kim,

  Roles Data curation, Investigation, Methodology, Supervision

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Edison Q. Kim,

  Roles Data curation, Investigation, Supervision

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Alexandria Jansen,

  Roles Investigation, Methodology, Supervision

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Katherine Li,

  Roles Investigation, Methodology

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• May Chan,

  Roles Data curation, Investigation, Methodology

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  http://orcid.org/0000-0002-7262-3632

  ⨯
• Brendan T. Keenan,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Jose Conejo-Garcia,

  Roles Conceptualization, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Diane C. Lim

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: limdiane@PennMedicine.upenn.edu

  Affiliations Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America

  http://orcid.org/0000-0001-5748-629X

  ⨯