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Open Access
Peer-reviewed
Research Article
Targeting mTOR and Src restricts hepatocellular carcinoma growth in a novel murine liver cancer model
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Sarah Walker,
Roles Investigation, Writing – original draft
Affiliations Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia, Gastroenterology and Hepatology Unit, The Canberra Hospital, Woden, Australia
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Miriam Wankell,
Roles Data curation, Methodology
Affiliation Department of Molecular and Cell Biology, Centre for Molecular Therapeutics, James Cook University, Australian Institute of Tropical Health and Medicine, Townsville, Australia
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Vikki Ho,
Roles Data curation
Affiliation Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia
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Rose White,
Roles Data curation
Affiliation Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia
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Nikita Deo,
Roles Data curation
Affiliation Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia
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Carol Devine,
Roles Data curation
Affiliation Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia
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Brittany Dewdney,
Roles Data curation
Affiliation Department of Molecular and Cell Biology, Centre for Molecular Therapeutics, James Cook University, Australian Institute of Tropical Health and Medicine, Townsville, Australia
⨯ - Prithi Bhathal,
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Olivier Govaere,
Roles Data curation
Affiliations Translational Cell and Tissue Research, Department of Imaging and Pathology, KULeuven and University Hospitals Leuven, Leuven, Belgium, Liver Research Group, Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle-upon-Tyne, United Kingdom
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Tania Roskams,
Roles Data curation
Affiliation Translational Cell and Tissue Research, Department of Imaging and Pathology, KULeuven and University Hospitals Leuven, Leuven, Belgium
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Liang Qiao,
Roles Conceptualization
Affiliation Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia
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Jacob George,
Roles Conceptualization, Funding acquisition, Writing – review & editing
Affiliation Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia
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Lionel Hebbard
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: lionel.hebbard@jcu.edu.au
Affiliations Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Westmead, Australia, Department of Molecular and Cell Biology, Centre for Molecular Therapeutics, James Cook University, Australian Institute of Tropical Health and Medicine, Townsville, Australia
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Targeting mTOR and Src restricts hepatocellular carcinoma growth in a novel murine liver cancer model
- Sarah Walker,
- Miriam Wankell,
- Vikki Ho,
- Rose White,
- Nikita Deo,
- Carol Devine,
- Brittany Dewdney,
- Prithi Bhathal,
- Olivier Govaere,
- Tania Roskams
- Published: February 22, 2019
- https://doi.org/10.1371/journal.pone.0212860