Overcoming the pitfalls of automatic interpretation of whole genome sequencing data by online tools for the prediction of pyrazinamide resistance in Mycobacterium tuberculosis

• Tomotada Iwamoto ,

  Contributed equally to this work with: Tomotada Iwamoto, Yoshiro Murase

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: tomotada_iwamoto@office.city.kobe.lg.jp (TI); mitarai@jata.or.jp (SM)

  Affiliation Department of Infectious Diseases, Kobe Institute of Health, Kobe City, Japan

  http://orcid.org/0000-0002-2650-0308

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• Yoshiro Murase ,

  Contributed equally to this work with: Tomotada Iwamoto, Yoshiro Murase

  Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

  Affiliation Bacteriology Division, Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose City, Tokyo, Japan

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• Shiomi Yoshida,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Clinical Research Center, National Hospital Organization Kinki-chuo Chest Medical Center, Sakai City, Osaka, Japan

  http://orcid.org/0000-0002-8197-3829

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• Akio Aono,

  Roles Formal analysis, Writing – review & editing

  Affiliation Bacteriology Division, Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose City, Tokyo, Japan

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• Makoto Kuroda,

  Roles Data curation, Software, Supervision, Writing – review & editing

  Affiliation Pathogen Genomics Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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• Tsuyoshi Sekizuka,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Pathogen Genomics Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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• Akifumi Yamashita,

  Roles Data curation, Methodology

  Affiliation Pathogen Genomics Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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• Kengo Kato,

  Roles Data curation, Methodology

  Affiliation Pathogen Genomics Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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• Takemasa Takii,

  Roles Data curation, Formal analysis

  Affiliation Molecular Epidemiology Division, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose City, Tokyo, Japan

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• Kentaro Arikawa,

  Roles Data curation, Formal analysis

  Affiliation Department of Infectious Diseases, Kobe Institute of Health, Kobe City, Japan

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• Seiya Kato,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose City, Tokyo, Japan

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• Satoshi Mitarai

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: tomotada_iwamoto@office.city.kobe.lg.jp (TI); mitarai@jata.or.jp (SM)

  Affiliations Bacteriology Division, Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose City, Tokyo, Japan, Basic Mycobacteriosis, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Nagasaki, Japan

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