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Open Access
Peer-reviewed
Research Article
Impact of a selective cyclooxygenase-2 inhibitor, celecoxib, on cortical excitability and electrophysiological properties of the brain in healthy volunteers: A randomized, double-blind, placebo-controlled study
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Jung-Ah Lim,
Roles Formal analysis, Investigation, Writing – original draft
Affiliations Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea, Department of Neurology, Gangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea
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Ki-Young Jung ,
Roles Conceptualization, Formal analysis, Visualization, Writing – review & editing
* E-mail: ideopki@gmail.com (KIP); jungky10@gmail.com (KYJ)
Affiliation Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea
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Boram Park,
Roles Formal analysis
Affiliation Department of Public Health Science, Seoul National University, Seoul, Korea
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Tae-Joon Kim,
Roles Formal analysis, Investigation
Affiliations Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea, Department of Neurology, Ajou University School of Medicine, Suwon, South Korea
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Jin-Sun Jun,
Roles Formal analysis, Investigation
Affiliations Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea, Department of Neurology, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, South Korea
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Keun Tae Kim,
Roles Formal analysis, Investigation
Affiliation Department of Neurology, Keimyung University Dongsan Medical Center, Daegu, South Korea
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Tae-Won Yang,
Roles Formal analysis, Investigation
Affiliation Department of Neurology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, South Korea
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Soon-Tae Lee,
Roles Formal analysis
Affiliation Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea
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Keun-Hwa Jung,
Roles Formal analysis
Affiliation Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea
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Kon Chu,
Roles Conceptualization, Formal analysis
Affiliation Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea
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Sang Kun Lee,
Roles Conceptualization, Formal analysis
Affiliation Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea
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Kyung-Il Park
Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing
* E-mail: ideopki@gmail.com (KIP); jungky10@gmail.com (KYJ)
Affiliations Department of Neurology, Comprehensive Epilepsy Center, Laboratory for Neurotherapeutics, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea, Department of Neurology, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, South Korea
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Impact of a selective cyclooxygenase-2 inhibitor, celecoxib, on cortical excitability and electrophysiological properties of the brain in healthy volunteers: A randomized, double-blind, placebo-controlled study
- Jung-Ah Lim,
- Ki-Young Jung,
- Boram Park,
- Tae-Joon Kim,
- Jin-Sun Jun,
- Keun Tae Kim,
- Tae-Won Yang,
- Soon-Tae Lee,
- Keun-Hwa Jung,
- Kon Chu
- Published: February 22, 2019
- https://doi.org/10.1371/journal.pone.0212689