Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function

• Jean J. Kim ,

  Contributed equally to this work with: Jean J. Kim, Jeffrey N. Savas

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jean.kim@bcm.edu (JJK); jeffrey.savas@northwestern.edu (JNS)

  Current address: Department of Molecular and Cellular Biology, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, United States of America

  Affiliations Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America, Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

  http://orcid.org/0000-0003-4709-262X

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• Jeffrey N. Savas ,

  Contributed equally to this work with: Jean J. Kim, Jeffrey N. Savas

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jean.kim@bcm.edu (JJK); jeffrey.savas@northwestern.edu (JNS)

  Current address: Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

  Affiliation Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Meghan T. Miller,

  Roles Investigation, Methodology, Validation

  Affiliation Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland

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• Xindao Hu,

  Roles Formal analysis, Investigation, Methodology, Validation

  Affiliations Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America, Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• Cassiano Carromeu,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• Mathieu Lavallée-Adam,

  Roles Formal analysis

  Affiliation Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Beatriz C. G. Freitas,

  Roles Investigation, Methodology

  Affiliation Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• Alysson R. Muotri,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America

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• John R. Yates III,

  Roles Funding acquisition, Methodology, Resources, Supervision

  Affiliation Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Anirvan Ghosh

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Current address: Research and Early Development, Biogen, Cambridge, Massachusetts, United States of America

  Affiliations Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America, Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland

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