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Open Access
Peer-reviewed
Research Article
The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner
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Cecilia Arriagada ,
Contributed equally to this work with: Cecilia Arriagada, Charlotte Luchsinger
Roles Formal analysis, Investigation, Methodology, Writing – original draft
Current address: Institute for Research in Dental Sciences, Faculty of Dentistry, Universidad de Chile, Santiago, Chile
Affiliations Department of Physiology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile, Center for Interdisciplinary Studies of the Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile
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Charlotte Luchsinger ,
Contributed equally to this work with: Cecilia Arriagada, Charlotte Luchsinger
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Department of Physiology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile, Center for Interdisciplinary Studies of the Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile
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Alexis E. González,
Roles Investigation, Methodology, Writing – review & editing
Current address: Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany
Affiliations Department of Physiology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile, Center for Interdisciplinary Studies of the Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile, Fundación Ciencia y Vida, Santiago, Chile
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Tomás Schwenke,
Roles Investigation, Methodology
Affiliation Departmento de Ciencias Biologicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Viña del Mar, Chile
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Gloria Arriagada,
Roles Funding acquisition, Methodology, Supervision, Writing – review & editing
Affiliation Departmento de Ciencias Biologicas, Facultad de Ciencias de la Vida, Universidad Andres Bello, Viña del Mar, Chile
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Hugo Folch,
Roles Methodology, Resources, Supervision
Affiliation Department of Immunology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile
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Pamela Ehrenfeld,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing
Affiliations Center for Interdisciplinary Studies of the Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile, Department of Anatomy, Histology and Pathology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile
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Patricia V. Burgos,
Roles Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing
Affiliations Department of Physiology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile, Center for Cell Biology and Biomedicine, School of Science and Medicine, Universidad San Sebastián, Santiago, Chile, Center for Aging and Regeneration (CARE), Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile
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Gonzalo A. Mardones
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft
* E-mail: gonzalo.mardones@uach.cl
Affiliations Department of Physiology, School of Medicine, Universidad Austral de Chile, Valdivia, Chile, Center for Interdisciplinary Studies of the Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile, Center for Cell Biology and Biomedicine, School of Science and Medicine, Universidad San Sebastián, Santiago, Chile
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The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner
- Cecilia Arriagada,
- Charlotte Luchsinger,
- Alexis E. González,
- Tomás Schwenke,
- Gloria Arriagada,
- Hugo Folch,
- Pamela Ehrenfeld,
- Patricia V. Burgos,
- Gonzalo A. Mardones
- Published: February 19, 2019
- https://doi.org/10.1371/journal.pone.0212321