Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer’s disease: Pooled analysis from 5 cohorts

• Galit Weinstein ,

  Roles Conceptualization, Investigation, Methodology, Project administration, Writing – original draft

  * E-mail: gweinstei@univ.haifa.ac.il

  Affiliation School of Public Health, University of Haifa, Haifa, Israel

  http://orcid.org/0000-0002-1316-4448

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• Kendra L. Davis-Plourde,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Framingham Heart Study, Framingham, MA, United States of America, Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America

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• Sarah Conner,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Framingham Heart Study, Framingham, MA, United States of America, Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America

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• Jayandra J. Himali,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Framingham Heart Study, Framingham, MA, United States of America, Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America, Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America

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• Alexa S. Beiser,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliations Framingham Heart Study, Framingham, MA, United States of America, Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America, Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America

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• Anne Lee,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology & Biostatistics, University of California, San Francisco, California, United States of America

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• Andreea M. Rawlings,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America

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• Sanaz Sedaghat,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands

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• Jie Ding,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States of America

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• Erin Moshier,

  Roles Formal analysis, Methodology

  Affiliation Icahn School of Medicine at Mount Sinai, New York, NY, United States of America

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• Cornelia M. van Duijn,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands

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• Michal S. Beeri,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Icahn School of Medicine at Mount Sinai, New York, NY, United States of America, The Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel HaShomer, Israel

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• Elizabeth Selvin,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

  http://orcid.org/0000-0001-6923-7151

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• M. Arfan Ikram,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands, Department of Radiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands

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• Lenore J. Launer,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliation Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States of America

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• Mary N. Haan,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology & Biostatistics, University of California, San Francisco, California, United States of America

  http://orcid.org/0000-0001-9312-4501

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•  [ ... ],
• Sudha Seshadri

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliations Framingham Heart Study, Framingham, MA, United States of America, Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America

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