Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia

• Laurent M. A. Favié ,

  Roles Data curation, Formal analysis, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lfavie@umcutrecht.nl

  Affiliations Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands

  http://orcid.org/0000-0002-4894-5236

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• Floris Groenendaal,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

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• Marcel P. H. van den Broek,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Writing – review & editing

  Affiliations Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, the Netherlands

  ⨯
• Carin M. A. Rademaker,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands

  ⨯
• Timo R. de Haan,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, Emma Children’s Hospital, Academic Medical Center, Amsterdam, the Netherlands

  ⨯
• Henrica L. M. van Straaten,

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, Isala Clinics, Zwolle, the Netherlands

  ⨯
• Peter H. Dijk,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, Groningen University Medical Centre, Groningen, the Netherlands

  ⨯
• Arno van Heijst,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, Radboud university medical center-Amalia Children’s Hospital, Nijmegen, the Netherlands

  ⨯
• Jeroen Dudink,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Neonatology, Erasmus Medical Centre-Sophia Children’s Hospital, Rotterdam, the Netherlands

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• Koen P. Dijkman,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, Máxima Medical Center Veldhoven, Veldhoven, the Netherlands

  ⨯
• Monique Rijken,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, Leiden University Medical Center, Leiden, the Netherlands

  ⨯
• Inge A. Zonnenberg,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, VU University Medical Center, Amsterdam, the Netherlands

  ⨯
• Filip Cools,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, UZ Brussel—Vrije Universiteit Brussel, Brussels, Belgium

  ⨯
• Alexandra Zecic,

  Roles Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neonatology, University Hospital Gent, Gent, Belgium

  ⨯
• Johanna H. van der Lee,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  Affiliation Paediatric Clinical Research Office, Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Debbie H. G. M. Nuytemans,

  Roles Project administration, Resources, Software, Writing – review & editing

  Affiliation Clinical Research Coordinator PharmaCool Study, Amsterdam, the Netherlands

  ⨯
• Frank van Bel,

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands

  ⨯
• Toine C. G. Egberts,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, the Netherlands

  ⨯
• Alwin D. R. Huitema,

  Roles Data curation, Formal analysis, Investigation, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliations Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Pharmacy & Pharmacology, Netherlands Cancer Institute, Amsterdam, the Netherlands

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•  [ ... ],
• on behalf of the PharmaCool study group

  ¶A complete list of non-author contributors appears in the Acknowledgments section.

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