How low can you go: What is the safe threshold for platelet transfusions in patients with hematologic malignancy in sub-Saharan Africa

Henry Ddungu; Elizabeth M. Krantz; Isaac Kajja; Sandra Naluzze; Hanifah Nabbanja; Flavia Nalubwama; Warren Phipps; Jackson Orem; Noah Kiwanuka; Anna Wald

doi:10.1371/journal.pone.0211648

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Open Access

Peer-reviewed

Research Article

How low can you go: What is the safe threshold for platelet transfusions in patients with hematologic malignancy in sub-Saharan Africa

Henry Ddungu ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Writing – original draft, Writing – review & editing

* E-mail: hddungu@fredhutch.org

Affiliation Uganda Cancer Institute, Upper Mulago Hill Road, Kampala, Uganda

http://orcid.org/0000-0001-9227-4030

⨯
Elizabeth M. Krantz,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America
⨯
Isaac Kajja,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation School of Medicine, College of Health Sciences, Makerere University Kampala, Uganda
⨯
Sandra Naluzze,

Roles Data curation, Project administration, Writing – review & editing

Affiliation Uganda Cancer Institute, Upper Mulago Hill Road, Kampala, Uganda
⨯
Hanifah Nabbanja,

Roles Data curation, Project administration, Writing – review & editing

Affiliation Uganda Cancer Institute, Upper Mulago Hill Road, Kampala, Uganda
⨯
Flavia Nalubwama,

Roles Data curation, Resources, Writing – review & editing

Affiliation Uganda Cancer Institute, Upper Mulago Hill Road, Kampala, Uganda
⨯
Warren Phipps,

Roles Conceptualization, Funding acquisition, Writing – review & editing

Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America, Department of Medicine, University of Washington, Seattle, WA, United States of America
⨯
Jackson Orem,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Uganda Cancer Institute, Upper Mulago Hill Road, Kampala, Uganda
⨯
Noah Kiwanuka,

Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

Affiliation School of Public Health, College of Health Sciences, Makerere University Kampala, Uganda
⨯
Anna Wald

Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America, Department of Medicine, University of Washington, Seattle, WA, United States of America, Department of Laboratory Medicine, University of Washington, Seattle, WA, United States of America, Department of Epidemiology, University of Washington, Seattle, WA, United States of America
⨯

How low can you go: What is the safe threshold for platelet transfusions in patients with hematologic malignancy in sub-Saharan Africa

Henry Ddungu,
Elizabeth M. Krantz,
Isaac Kajja,
Sandra Naluzze,
Hanifah Nabbanja,
Flavia Nalubwama,
Warren Phipps,
Jackson Orem,
Noah Kiwanuka,
Anna Wald

Published: February 6, 2019
https://doi.org/10.1371/journal.pone.0211648

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Blood transfusion
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Hematologic cancers and related disorders
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