Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

• Makiko Shinomoto,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

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• Takashi Kasai ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – original draft, Writing – review & editing

  * E-mail: kasaita@koto.kpu-m.ac.jp

  Affiliation Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

  http://orcid.org/0000-0002-6424-0738

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• Harutsugu Tatebe,

  Roles Data curation, Investigation

  Affiliations Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan, Department of Zaitaku (Homecare) Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan

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• Masaki Kondo,

  Roles Investigation, Resources

  Affiliation Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

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• Takuma Ohmichi,

  Roles Investigation, Resources

  Affiliation Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

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• Masafumi Morimoto,

  Roles Conceptualization, Resources

  Affiliation Department of Pediatrics, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

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• Tomohiro Chiyonobu,

  Roles Conceptualization, Resources

  Affiliations Department of Pediatrics, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan, Department of Pediatrics, North Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan

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• Naoto Terada,

  Roles Resources

  Affiliation Hananoki Medical Welfare Center, Kyoto, Japan

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• David Allsop,

  Roles Supervision, Writing – review & editing

  Affiliation Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom

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• Isao Yokota,

  Roles Formal analysis, Methodology

  Affiliation Department of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto, Japan

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• Toshiki Mizuno,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

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• Takahiko Tokuda

  Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing

  Affiliations Department of Neurology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan, Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine, Kyoto, Japan

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