MALDI imaging mass spectrometry revealed atropine distribution in the ocular tissues and its transit from anterior to posterior regions in the whole-eye of rabbit after topical administration

• Naoto Mori ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: naoto.mori@santen.com

  Affiliation Nara Research and Development Center, Santen Pharmaceutical Co., Ltd., Ikoma-shi, Nara, Japan

  http://orcid.org/0000-0001-6454-0418

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• Takaharu Mochizuki,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Nara Research and Development Center, Santen Pharmaceutical Co., Ltd., Ikoma-shi, Nara, Japan

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• Fumiyoshi Yamazaki,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan, International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan

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• Shiro Takei,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Laboratory of Fish Biology, Department of Environmental Biology, College of Bioscience and Biotechnology, Chubu University, Kasugai, Aichi, Japan

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• Hidetoshi Mano,

  Roles Conceptualization, Writing – review & editing

  Affiliation Nara Research and Development Center, Santen Pharmaceutical Co., Ltd., Ikoma-shi, Nara, Japan

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• Takeshi Matsugi,

  Roles Conceptualization, Writing – review & editing

  Affiliation Nara Research and Development Center, Santen Pharmaceutical Co., Ltd., Ikoma-shi, Nara, Japan

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• Mitsutoshi Setou

  Roles Conceptualization, Project administration, Supervision, Writing – review & editing

  Affiliations Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan, International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan, Department of Systems Molecular Anatomy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education & Research Center, Hamamatsu, Shizuoka, Japan, Department of Anatomy, The university of Hong Kong, Pokfulam, Hong Kong SAR, China

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