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Open Access
Peer-reviewed
Research Article
Label-free classification of cells based on supervised machine learning of subcellular structures
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Yusuke Ozaki ,
Contributed equally to this work with: Yusuke Ozaki, Hidenao Yamada
Roles Conceptualization, Investigation, Writing – original draft
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Hidenao Yamada ,
Contributed equally to this work with: Yusuke Ozaki, Hidenao Yamada
Roles Conceptualization, Data curation, Visualization, Writing – original draft
* E-mail: iwai@crl.hpk.co.jp
Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu, Shizuoka, Japan
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Hirotoshi Kikuchi,
Roles Conceptualization, Funding acquisition, Writing – review & editing
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Amane Hirotsu,
Roles Investigation
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Tomohiro Murakami,
Roles Resources
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Tomohiro Matsumoto,
Roles Resources
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Toshiki Kawabata,
Roles Funding acquisition
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Yoshihiro Hiramatsu,
Roles Resources
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Kinji Kamiya,
Roles Resources
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Toyohiko Yamauchi,
Roles Data curation, Methodology
Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu, Shizuoka, Japan
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Kentaro Goto,
Roles Resources
Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu, Shizuoka, Japan
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Yukio Ueda,
Roles Supervision
Affiliation Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu, Shizuoka, Japan
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Shigetoshi Okazaki,
Roles Supervision
Affiliation Department of Medical Spectroscopy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Masatoshi Kitagawa,
Roles Supervision
Affiliations Department of Molecular Biology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan, Laboratory Animal Facilities and Services, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Hiroya Takeuchi,
Roles Supervision
Affiliation Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Hiroyuki Konno
Roles Funding acquisition, Project administration
Affiliation Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan
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Label-free classification of cells based on supervised machine learning of subcellular structures
- Yusuke Ozaki,
- Hidenao Yamada,
- Hirotoshi Kikuchi,
- Amane Hirotsu,
- Tomohiro Murakami,
- Tomohiro Matsumoto,
- Toshiki Kawabata,
- Yoshihiro Hiramatsu,
- Kinji Kamiya,
- Toyohiko Yamauchi
- Published: January 29, 2019
- https://doi.org/10.1371/journal.pone.0211347