Determination of blood dexmedetomidine in dried blood spots by LC-MS/MS to screen therapeutic levels in paediatric patients

• Liliana Rivera-Espinosa ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Conceptualization, Formal analysis, Validation, Writing – original draft

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

  http://orcid.org/0000-0002-1334-0026

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• Alejandra Toledo-López ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Data curation, Formal analysis, Methodology

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

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• Juan Luis Chávez-Pacheco ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Formal analysis, Methodology, Validation, Writing – original draft

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

  http://orcid.org/0000-0001-6919-4497

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• Radamés Alemón-Medina ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

  http://orcid.org/0000-0001-8587-9330

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• Josefina Gómez-Garduño ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Data curation, Validation, Writing – original draft

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

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• Gustavo Lugo-Goytia ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Conceptualization, Data curation, Supervision, Writing – review & editing

  Affiliation Anaesthesiology and Critical Medicine Department, National Institute of Medical Sciences and Nutrition, Mexico City, Mexico, Intensive Care Unit, National Institute of Respiratory Diseases, Mexico City, Mexico

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• Raquel García-Álvarez ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Data curation, Methodology, Writing – original draft

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

  http://orcid.org/0000-0003-3563-134X

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• Hugo Juárez-Olguín ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Conceptualization, Supervision, Validation, Writing – original draft

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

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• Luz María Torres-Espíndola ,

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

  http://orcid.org/0000-0001-8689-9755

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• María-Gabriela Pérez-Guillé

  Contributed equally to this work with: Liliana Rivera-Espinosa, Alejandra Toledo-López, Juan Luis Chávez-Pacheco, Radamés Alemón-Medina, Josefina Gómez-Garduño, Gustavo Lugo-Goytia, Raquel García-Álvarez, Hugo Juárez-Olguín, Luz María Torres-Espíndola, María-Gabriela Pérez-Guillé

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: reparo_gaby@hotmail.com

  Affiliation Pharmacology Laboratory, National Institute of Paediatrics, Mexico City, Mexico

  http://orcid.org/0000-0003-2448-7952

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