Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

• Tung-Cheng Chang,

  Roles Data curation, Investigation, Resources, Writing – review & editing

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Surgery, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of General Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan

  ⨯
• Po-Li Wei,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Writing – original draft

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Surgery, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of Colorectal Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, Cancer Research Center and Translational Laboratory, Department of Medical Research, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei, Taiwan

  http://orcid.org/0000-0002-7275-2661

  ⨯
• Precious Takondwa Makondi,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, International PhD Program in Medicine, Taipei Medical University, Taipei, Taiwan

  ⨯
• Wei-Ting Chen,

  Roles Investigation

  Affiliation Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

  ⨯
• Chien-Yu Huang ,

  Roles Data curation, Funding acquisition, Investigation, Project administration, Resources, Validation, Writing – original draft

  * E-mail: cyh@tmu.edu.tw(CH);r5424012@tmu.edu.tw(YC)

  Affiliations Department of Surgery, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of General Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan

  ⨯
• Yu-Jia Chang

  Roles Conceptualization, Data curation, Formal analysis, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: cyh@tmu.edu.tw(CH);r5424012@tmu.edu.tw(YC)

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Cancer Research Center and Translational Laboratory, Department of Medical Research, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, International PhD Program in Medicine, Taipei Medical University, Taipei, Taiwan

  http://orcid.org/0000-0003-3978-3244

  ⨯