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Open Access
Peer-reviewed
Research Article
A single nucleotide polymorphism in dopamine beta hydroxylase (rs6271(C>T)) is over-represented in inflammatory bowel disease patients and reduces circulating enzyme
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Eugene Gonzalez-Lopez,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft
Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
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Yuka Kawasawa-Imamura,
Roles Data curation, Formal analysis, Methodology, Software, Validation
Affiliations Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America, Genome Sciences Core Facility, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
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Lijun Zhang,
Roles Formal analysis, Validation, Writing – review & editing
Affiliations Genome Sciences Core Facility, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
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Xuemei Huang,
Roles Formal analysis, Funding acquisition, Resources, Writing – review & editing
Affiliations Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America, Department of Neurology, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States of America, Departments of Neurology, Neurosurgery and Radiology, Milton S. Hershey Medical Center, and Kinesiology, Pennsylvania State University, Hershey, Pennsylvania, United States of America
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Walter A. Koltun,
Roles Funding acquisition, Resources
Affiliation Department of Surgery, Division of Colon and Rectal Surgery, Pennsylvania State University, Hershey, Pennsylvania, United States of America
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Matthew D. Coates ,
Contributed equally to this work with: Matthew D. Coates, Kent E. Vrana
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: kvrana@pennstatehealth.psu.edu (KV); mcoates@pennstatehealth.psu.edu (MC)
Affiliation Department of Medicine, Division of Gastroenterology & Hepatology, Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America
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Kent E. Vrana
Contributed equally to this work with: Matthew D. Coates, Kent E. Vrana
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: kvrana@pennstatehealth.psu.edu (KV); mcoates@pennstatehealth.psu.edu (MC)
Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
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A single nucleotide polymorphism in dopamine beta hydroxylase (rs6271(C>T)) is over-represented in inflammatory bowel disease patients and reduces circulating enzyme
- Eugene Gonzalez-Lopez,
- Yuka Kawasawa-Imamura,
- Lijun Zhang,
- Xuemei Huang,
- Walter A. Koltun,
- Matthew D. Coates,
- Kent E. Vrana
- Published: February 28, 2019
- https://doi.org/10.1371/journal.pone.0210175