Holistic engineering of Cal-A lipase chain-length selectivity identifies triglyceride binding hot-spot

Daniela Quaglia; Lorea Alejaldre; Sara Ouadhi; Olivier Rousseau; Joelle N. Pelletier

doi:10.1371/journal.pone.0210100

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Peer-reviewed

Research Article

Holistic engineering of Cal-A lipase chain-length selectivity identifies triglyceride binding hot-spot

Daniela Quaglia,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Département de Chimie and Center for Green Chemistry and Catalysis (CGCC), Université de Montréal, Montréal, QC, Canada, PROTEO, The Québec Network for Research on Protein Function, Engineering and Applications, Québec, QC, Canada
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Lorea Alejaldre,

Roles Data curation, Formal analysis, Methodology, Validation, Writing – review & editing

Affiliations PROTEO, The Québec Network for Research on Protein Function, Engineering and Applications, Québec, QC, Canada, Département de Biochimie, Université de Montréal, Montréal, QC, Canada
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Sara Ouadhi,

Roles Formal analysis, Investigation

Affiliations Département de Chimie and Center for Green Chemistry and Catalysis (CGCC), Université de Montréal, Montréal, QC, Canada, PROTEO, The Québec Network for Research on Protein Function, Engineering and Applications, Québec, QC, Canada
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Olivier Rousseau,

Roles Data curation, Methodology

Affiliations Département de Chimie and Center for Green Chemistry and Catalysis (CGCC), Université de Montréal, Montréal, QC, Canada, PROTEO, The Québec Network for Research on Protein Function, Engineering and Applications, Québec, QC, Canada
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Joelle N. Pelletier

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: joelle.pelletier@umontreal.ca

Affiliations Département de Chimie and Center for Green Chemistry and Catalysis (CGCC), Université de Montréal, Montréal, QC, Canada, PROTEO, The Québec Network for Research on Protein Function, Engineering and Applications, Québec, QC, Canada, Département de Biochimie, Université de Montréal, Montréal, QC, Canada

http://orcid.org/0000-0002-2934-6940

⨯

Holistic engineering of Cal-A lipase chain-length selectivity identifies triglyceride binding hot-spot

Daniela Quaglia,
Lorea Alejaldre,
Sara Ouadhi,
Olivier Rousseau,
Joelle N. Pelletier

Published: January 14, 2019
https://doi.org/10.1371/journal.pone.0210100

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