The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma

• S. Di Matteo,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Visualization, Writing – original draft

  Affiliation Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

  http://orcid.org/0000-0002-2586-7159

  ⨯
• L. Nevi ,

  Contributed equally to this work with: L. Nevi, D. Costantini

  Roles Methodology

  Affiliation Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

  http://orcid.org/0000-0003-0924-2551

  ⨯
• D. Costantini ,

  Contributed equally to this work with: L. Nevi, D. Costantini

  Roles Methodology

  Affiliation Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

  ⨯
• D. Overi,

  Roles Methodology

  Affiliation Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Rome, Italy

  http://orcid.org/0000-0003-3561-8903

  ⨯
• G. Carpino,

  Roles Methodology

  Affiliation Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome "Foro Italico", Rome, Italy

  ⨯
• S. Safarikia,

  Roles Methodology

  Affiliation Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

  ⨯
• F. Giulitti,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software

  Affiliation Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome "Foro Italico", Rome, Italy

  ⨯
• C. Napoletano,

  Roles Methodology

  Affiliation Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy

  ⨯
• E. Manzi,

  Roles Resources

  Affiliation Gastroenterology Unit, Regina Elena National Cancer Institute, Rome, Italy

  ⨯
• A. M. De Rose,

  Roles Resources

  Affiliation Hepatobiliary Unit, Catholic University of the Sacred Heart School of Medicine, Rome, Italy

  ⨯
• F. Melandro,

  Roles Resources

  Affiliation Department of General Surgery and Organ Transplantation, Sapienza University of Rome, Rome, Italy

  ⨯
• M. Bragazzi,

  Roles Resources

  Affiliation Medical-Surgical and Biotechnologies Sciences, Polo Pontino, Sapienza University of Rome, Rome, Italy

  ⨯
• P. B. Berloco,

  Roles Resources

  Affiliation Department of General Surgery and Organ Transplantation, Sapienza University of Rome, Rome, Italy

  ⨯
• F. Giuliante,

  Roles Resources

  Affiliation Hepatobiliary Unit, Catholic University of the Sacred Heart School of Medicine, Rome, Italy

  ⨯
• G. Grazi,

  Roles Resources

  Affiliation Gastroenterology Unit, Regina Elena National Cancer Institute, Rome, Italy

  http://orcid.org/0000-0002-3279-0313

  ⨯
• A. Giorgi,

  Roles Visualization

  Affiliation Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

  ⨯
• V. Cardinale,

  Roles Resources

  Affiliation Medical-Surgical and Biotechnologies Sciences, Polo Pontino, Sapienza University of Rome, Rome, Italy

  ⨯
• L. Adorini,

  Roles Supervision, Visualization

  Affiliation Intercept Pharmaceuticals, New York, New York, United States of America

  http://orcid.org/0000-0001-8109-339X

  ⨯
• E. Gaudio,

  Roles Funding acquisition

  Affiliation Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, Rome, Italy

  ⨯
•  [ ... ],
• D. Alvaro

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: domenico.alvaro@uniroma1.it

  Affiliation Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

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