Development of the covalent antibody-DNA conjugates technology for detection of IgE and IgM antibodies by immuno-PCR

Artem V. Maerle; Maria A. Simonova; Victor D. Pivovarov; Daria V. Voronina; Polina E. Drobyazina; Dmitriy Yu. Trofimov; Leonid P. Alekseev; Sergei K. Zavriev; Dmitriy Yu. Ryazantsev

doi:10.1371/journal.pone.0209860

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Open Access

Peer-reviewed

Research Article

Development of the covalent antibody-DNA conjugates technology for detection of IgE and IgM antibodies by immuno-PCR

Artem V. Maerle ,

Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

* E-mail: maerle@yandex.ru

Affiliation OOO DNA-Technology TS, Moscow, Russia

http://orcid.org/0000-0003-1184-4965

⨯
Maria A. Simonova,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
⨯
Victor D. Pivovarov,

Roles Investigation

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
⨯
Daria V. Voronina,

Roles Investigation

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
⨯
Polina E. Drobyazina,

Roles Investigation, Writing – review & editing

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
⨯
Dmitriy Yu. Trofimov,

Roles Supervision, Writing – review & editing

Affiliation Federal state budget institution “National medical research center for obstetrics, gynecology and perinatology named after academician V.I. Kulakov” of the Ministry of healthcare of Russian Federation, Moscow, Russia
⨯
Leonid P. Alekseev,

Roles Supervision, Writing – review & editing

Affiliation NRC Institute of Immunology, Federal Biomedical Agency of Russia, Moscow, Russia
⨯
Sergei K. Zavriev,

Roles Supervision, Writing – review & editing

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
⨯
Dmitriy Yu. Ryazantsev

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
⨯

Development of the covalent antibody-DNA conjugates technology for detection of IgE and IgM antibodies by immuno-PCR

Artem V. Maerle,
Maria A. Simonova,
Victor D. Pivovarov,
Daria V. Voronina,
Polina E. Drobyazina,
Dmitriy Yu. Trofimov,
Leonid P. Alekseev,
Sergei K. Zavriev,
Dmitriy Yu. Ryazantsev

Published: January 4, 2019
https://doi.org/10.1371/journal.pone.0209860

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