Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung

• Maike Thamsen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Diabetes Center, University of California, San Francisco, California, United States of America, Quantitative Biosciences Institute (QBI), University of California, San Francisco, California, United States of America, Lung Biology Center, University of California, San Francisco, California, United States of America

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• Rajarshi Ghosh,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Diabetes Center, University of California, San Francisco, California, United States of America, Quantitative Biosciences Institute (QBI), University of California, San Francisco, California, United States of America, Lung Biology Center, University of California, San Francisco, California, United States of America

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• Vincent C. Auyeung,

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Lung Biology Center, University of California, San Francisco, California, United States of America, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, California, United States of America

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• Alexis Brumwell,

  Roles Data curation, Investigation

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, California, United States of America, Cardiovascular Research Institute, University of California, San Francisco, California, United States of America

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• Harold A. Chapman,

  Roles Data curation, Supervision

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, California, United States of America, Cardiovascular Research Institute, University of California, San Francisco, California, United States of America

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• Bradley J. Backes,

  Roles Investigation, Methodology

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Diabetes Center, University of California, San Francisco, California, United States of America, Lung Biology Center, University of California, San Francisco, California, United States of America

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• Gayani Perara,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Chemistry and Department of Biochemistry, University of Washington, Seattle, Washington, United States of America

  http://orcid.org/0000-0002-6982-4863

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• Dustin J. Maly,

  Roles Conceptualization, Supervision

  Affiliation Department of Chemistry and Department of Biochemistry, University of Washington, Seattle, Washington, United States of America

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• Dean Sheppard,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Lung Biology Center, University of California, San Francisco, California, United States of America, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, California, United States of America

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• Feroz R. Papa

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: frpapa@medicine.ucsf.edu

  Affiliations Department of Medicine, University of California, San Francisco, California, United States of America, Diabetes Center, University of California, San Francisco, California, United States of America, Quantitative Biosciences Institute (QBI), University of California, San Francisco, California, United States of America, Lung Biology Center, University of California, San Francisco, California, United States of America, Department of Pathology, University of California, San Francisco, California, United States of America

  http://orcid.org/0000-0001-6273-1595

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