An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z

• Yan Wang,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Murat C. Cobanoglu,

  Roles Conceptualization, Data curation, Formal analysis, Methodology

  Affiliation Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Jie Li,

  Roles Formal analysis, Methodology

  Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Tunda Hidvegi,

  Roles Formal analysis, Investigation, Methodology, Visualization

  Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

  http://orcid.org/0000-0002-0285-2480

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• Pamela Hale,

  Roles Investigation

  Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Michael Ewing,

  Roles Formal analysis, Investigation

  Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Andrew S. Chu,

  Roles Formal analysis, Methodology

  Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0002-8824-2914

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• Zhenwei Gong,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Radhika Muzumdar,

  Roles Formal analysis

  Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Stephen C. Pak,

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft

  Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Gary A. Silverman,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Ivet Bahar,

  Roles Conceptualization, Formal analysis, Writing – original draft

  Affiliation Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• David H. Perlmutter

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: perlmutterd@wustl.edu

  Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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