Glycosaminoglycans from Alzheimer’s disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau

Minh Bao Huynh; Mohand Ouidir Ouidja; Sandrine Chantepie; Gilles Carpentier; Auriane Maïza; Ganlin Zhang; Joao Vilares; Rita Raisman-Vozari; Dulce Papy-Garcia

doi:10.1371/journal.pone.0209573

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Open Access

Peer-reviewed

Research Article

Glycosaminoglycans from Alzheimer’s disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau

Minh Bao Huynh,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France
⨯
Mohand Ouidir Ouidja,

Roles Investigation, Writing – review & editing

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France
⨯
Sandrine Chantepie,

Roles Investigation, Writing – review & editing

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France
⨯
Gilles Carpentier,

Roles Methodology

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France
⨯
Auriane Maïza,

Roles Investigation, Writing – review & editing

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France
⨯
Ganlin Zhang,

Roles Investigation

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France
⨯
Joao Vilares,

Roles Resources

Affiliation Aging and Neurodegenerative Diseases Brain Bank Investigation Laboratory, Universidade Federal de São Paulo, São Paulo, Brazil
⨯
Rita Raisman-Vozari,

Roles Resources, Visualization

Affiliation Université Pierre et Marie Curie-Paris 6, Centre de Recherche de l’Institut du Cerveau et de la Moelle Epinière (CRICM), Paris, France
⨯
Dulce Papy-Garcia

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – original draft

* E-mail: papy@u-pec.fr

Affiliation Cell Growth, Tissue Repair and Regeneration (CRRET), UPEC EA 4397/ERL CNRS 9215, Université Paris Est Créteil, Université Paris Est, Créteil, France

http://orcid.org/0000-0003-2225-9331

⨯

Glycosaminoglycans from Alzheimer’s disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau

Minh Bao Huynh,
Mohand Ouidir Ouidja,
Sandrine Chantepie,
Gilles Carpentier,
Auriane Maïza,
Ganlin Zhang,
Joao Vilares,
Rita Raisman-Vozari,
Dulce Papy-Garcia

Published: January 4, 2019
https://doi.org/10.1371/journal.pone.0209573

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Growth factors
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Heparin
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Alzheimer's disease
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