Mechanisms of acquired resistance to afatinib clarified with liquid biopsy

• Tomomi Nakamura ,

  Contributed equally to this work with: Tomomi Nakamura, Chiho Nakashima

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Hematology, Respiratory Medicine and Oncology, Faculty of Medicine, Saga University, Saga, Japan

  http://orcid.org/0000-0003-1943-7352

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• Chiho Nakashima ,

  Contributed equally to this work with: Tomomi Nakamura, Chiho Nakashima

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Hematology, Respiratory Medicine and Oncology, Faculty of Medicine, Saga University, Saga, Japan

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• Kazutoshi Komiya,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Hematology, Respiratory Medicine and Oncology, Faculty of Medicine, Saga University, Saga, Japan

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• Kazuki Kitera,

  Roles Methodology, Writing – review & editing

  Affiliation ARKRAY Inc., Kyoto, Japan

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• Mitsuharu Hirai,

  Roles Methodology, Writing – review & editing

  Affiliation ARKRAY Inc., Kyoto, Japan

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• Shinya Kimura,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Internal Medicine, Division of Hematology, Respiratory Medicine and Oncology, Faculty of Medicine, Saga University, Saga, Japan

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• Naoko Aragane

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  * E-mail: sueokan@cc.saga-u.ac.jp

  Affiliation Department of Internal Medicine, Division of Hematology, Respiratory Medicine and Oncology, Faculty of Medicine, Saga University, Saga, Japan

  http://orcid.org/0000-0002-7428-9068

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