Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes

• Serena Pavoni,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft

  Affiliation Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France

  http://orcid.org/0000-0001-8722-088X

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• Rafika Jarray,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France, Sup'Biotech, Villejuif, France

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• Ferid Nassor,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France

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• Anne-Cécile Guyot,

  Roles Investigation

  Affiliation Laboratory of Drug Metabolism Research (LEMM), Institute of Biology and Technology Saclay (IBITECS), CEA, Université Paris-Saclay, Gif-sur-Yvette, France

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• Steve Cottin,

  Roles Investigation

  Affiliation Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France

  http://orcid.org/0000-0002-5339-0677

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• Jessica Rontard,

  Roles Investigation

  Affiliation Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France

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• Jacqueline Mikol,

  Roles Conceptualization, Writing – original draft

  Affiliation Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France

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• Aloïse Mabondzo,

  Roles Conceptualization, Methodology

  Affiliation Laboratory of Drug Metabolism Research (LEMM), Institute of Biology and Technology Saclay (IBITECS), CEA, Université Paris-Saclay, Gif-sur-Yvette, France

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• Jean-Philippe Deslys,

  Roles Funding acquisition, Project administration, Supervision, Writing – original draft

  Affiliation Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France

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• Frank Yates

  Roles Conceptualization, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: frank.yates@supbiotech.fr

  Affiliations Service d’Etude des Prions et Infections Atypiques (SEPIA), Institut François Jacob, CEA, Université Paris-Saclay, Fontenay-aux-Roses, France, Sup'Biotech, Villejuif, France

  http://orcid.org/0000-0002-3590-5745

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