Third harmonic generation imaging and analysis of the effect of low gravity on the lacuno-canalicular network of mouse bone

Rachel Genthial; Maude Gerbaix; Delphine Farlay; Laurence Vico; Emmanuel Beaurepaire; Delphine Débarre; Aurélien Gourrier

doi:10.1371/journal.pone.0209079

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Open Access

Peer-reviewed

Research Article

Third harmonic generation imaging and analysis of the effect of low gravity on the lacuno-canalicular network of mouse bone

Rachel Genthial,

Roles Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – review & editing

Current address: Department of Biology, McGill University, Montreal, Canada

Affiliation Univ. Grenoble Alpes, CNRS, LIPhy, Grenoble, France
⨯
Maude Gerbaix,

Roles Conceptualization, Project administration, Validation, Writing – review & editing

Affiliations INSERM U1059, Université de Lyon, St Etienne, France, French National Centre for Space Studies, Paris, France
⨯
Delphine Farlay,

Roles Methodology, Writing – review & editing

Affiliation INSERM, UMR1033, Université de Lyon, Lyon, France
⨯
Laurence Vico,

Roles Project administration, Validation, Writing – review & editing

Affiliation INSERM U1059, Université de Lyon, St Etienne, France
⨯
Emmanuel Beaurepaire,

Roles Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Writing – review & editing

Affiliation Lab. for Optics and Biosciences, Ecole Polytechnique, CNRS, INSERM, Palaiseau, France

http://orcid.org/0000-0002-2082-8214

⨯
Delphine Débarre ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: delphine.debarre@univ-grenoble-alpes.fr (DD); aurelien.gourrier@univ-grenoble-alpes.fr (AG)

Affiliation Univ. Grenoble Alpes, CNRS, LIPhy, Grenoble, France
⨯
Aurélien Gourrier

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: delphine.debarre@univ-grenoble-alpes.fr (DD); aurelien.gourrier@univ-grenoble-alpes.fr (AG)

Affiliation Univ. Grenoble Alpes, CNRS, LIPhy, Grenoble, France

http://orcid.org/0000-0001-9526-5746

⨯

Third harmonic generation imaging and analysis of the effect of low gravity on the lacuno-canalicular network of mouse bone

Rachel Genthial,
Maude Gerbaix,
Delphine Farlay,
Laurence Vico,
Emmanuel Beaurepaire,
Delphine Débarre,
Aurélien Gourrier

Published: January 2, 2019
https://doi.org/10.1371/journal.pone.0209079

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Bone imaging
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Fluorescence imaging
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Osteocytes
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