Corticosteroid use and increased CXCR2 levels on leukocytes are associated with lumacaftor/ivacaftor discontinuation in cystic fibrosis patients homozygous for the F508del CFTR mutation

• Kerstin Pohl,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, National Jewish Health, Denver, CO, United States of America

  http://orcid.org/0000-0002-0787-8620

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• David P. Nichols,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Pediatrics, University of Washington, Seattle, WA, United States of America

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• Jennifer L. Taylor-Cousar,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Medicine, National Jewish Health, Denver, CO, United States of America, Department of Pediatrics, National Jewish Health, Denver, CO, United States of America, University of Colorado School of Medicine, Aurora, CO, United States of America

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• Milene T. Saavedra,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliations Department of Medicine, National Jewish Health, Denver, CO, United States of America, University of Colorado School of Medicine, Aurora, CO, United States of America

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• Matthew J. Strand,

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Biostatistics and Bioinformatics, National Jewish Health, Denver, CO, United States of America

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• Jerry A. Nick ,

  Contributed equally to this work with: Jerry A. Nick, Preston E. Bratcher

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Medicine, National Jewish Health, Denver, CO, United States of America, University of Colorado School of Medicine, Aurora, CO, United States of America

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• Preston E. Bratcher

  Contributed equally to this work with: Jerry A. Nick, Preston E. Bratcher

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bratcherp@njhealth.org

  Affiliation Department of Pediatrics, National Jewish Health, Denver, CO, United States of America

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