Exploring the insulin secretory properties of the PGD₂-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients

• Stanko Skrtic ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: stanko.skrtic@astrazeneca.com

  Affiliations Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden, Department of Endocrinology, Sahlgrenska University Hospital and Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  http://orcid.org/0000-0002-1950-5418

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• Björn Tyrberg,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

  http://orcid.org/0000-0003-0976-1220

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• Malin Broberg,

  Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Hans Ericsson,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Volker Schnecke,

  Roles Data curation, Formal analysis, Software, Visualization, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Magnus Kjaer,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Marcus Hompesch,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation ProSciento Inc, Chula Vista, CA, United States of America

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• Eva-Marie Andersson,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Erik Ryberg,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Alexander Aivazidis,

  Roles Data curation, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Charlotte Wennberg Huldt,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Lars Löfgren,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Linda Morrow,

  Roles Conceptualization, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation ProSciento Inc, Chula Vista, CA, United States of America

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• Joanna Parkinson,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Tina Rydén-Bergsten,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

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• Elaine Watkins,

  Roles Data curation, Investigation, Methodology, Project administration

  Affiliation ProSciento Inc, Chula Vista, CA, United States of America

  http://orcid.org/0000-0002-6901-6567

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•  [ ... ],
• Maria Sörhede Winzell

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Cardiovascular, Renal and Metabolism, IMED Biotech Unit, AstraZeneca Gothenburg, Mölndal, Sweden

  http://orcid.org/0000-0003-3125-4858

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