Analysis of NK cell clones obtained using interleukin-2 and gene-modified K562 cells revealed the ability of “senescent” NK cells to lose CD57 expression and start expressing NKG2A

• Maria A. Streltsova,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Laboratory of Cell Interactions, Department of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation

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• Sofya A. Erokhina,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Laboratory of Cell Interactions, Department of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation

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• Leonid M. Kanevskiy,

  Roles Writing – review & editing

  Affiliation Laboratory of Cell Interactions, Department of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation

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• Dean A. Lee,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Center for Childhood Cancer and Blood Disorders, The Research Institute, Nationwide Children’s Hospital, Columbus, OH, United States of America

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• William G. Telford,

  Roles Conceptualization, Formal analysis, Resources, Supervision, Writing – review & editing

  Affiliation Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

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• Alexander M. Sapozhnikov,

  Roles Conceptualization

  Affiliation Laboratory of Cell Interactions, Department of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation

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• Elena I. Kovalenko

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: kovalenelen@gmail.com

  Affiliation Laboratory of Cell Interactions, Department of Immunology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russian Federation

  http://orcid.org/0000-0001-8119-8247

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