Tranexamic acid decreases rodent hemorrhagic shock-induced inflammation with mixed end-organ effects

Patrick F. Walker; Anthony D. Foster; Philip A. Rothberg; Thomas A. Davis; Matthew J. Bradley

doi:10.1371/journal.pone.0208249

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Open Access

Peer-reviewed

Research Article

Tranexamic acid decreases rodent hemorrhagic shock-induced inflammation with mixed end-organ effects

Patrick F. Walker ,

Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

* E-mail: Patrick.f.walker.mil@mail.mil

Affiliations Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America

http://orcid.org/0000-0002-0871-2702

⨯
Anthony D. Foster,

Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliations Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America
⨯
Philip A. Rothberg,

Roles Conceptualization, Data curation, Investigation

Affiliations Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America
⨯
Thomas A. Davis,

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

Affiliations Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America
⨯
Matthew J. Bradley

Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

Affiliations Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Department of Surgery, Uniformed Services University and Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America
⨯

Tranexamic acid decreases rodent hemorrhagic shock-induced inflammation with mixed end-organ effects

Patrick F. Walker,
Anthony D. Foster,
Philip A. Rothberg,
Thomas A. Davis,
Matthew J. Bradley

Published: November 29, 2018
https://doi.org/10.1371/journal.pone.0208249

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Rodents
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