RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation

• Rahyza I. F. Assis,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil

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• Malgorzata Wiench,

  Roles Funding acquisition, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation School of Dentistry, School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom

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• Karina G. Silvério,

  Roles Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil

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• Rodrigo A. da Silva,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, Biosciences Institute, São Paulo State University, Botucatu,São Paulo, Brazil

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• Geórgia da Silva Feltran,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Chemistry and Biochemistry, Biosciences Institute, São Paulo State University, Botucatu,São Paulo, Brazil

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• Enilson A. Sallum,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil

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• Marcio Z. Casati,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil

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• Francisco H. Nociti Jr,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil

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• Denise C. Andia

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: denise.andia@docente.unip.br

  Affiliations Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil, Division of Epigenetics, School of Dentistry, Health Science Institute, Paulista University, São Paulo, Brazil

  http://orcid.org/0000-0002-0049-0201

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