Automatic inference model construction for computer-aided diagnosis of lung nodule: Explanation adequacy, inference accuracy, and experts’ knowledge

Masami Kawagishi; Takeshi Kubo; Ryo Sakamoto; Masahiro Yakami; Koji Fujimoto; Gakuto Aoyama; Yutaka Emoto; Hiroyuki Sekiguchi; Koji Sakai; Yoshio Iizuka; Mizuho Nishio; Hiroyuki Yamamoto; Kaori Togashi

doi:10.1371/journal.pone.0207661

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Open Access

Peer-reviewed

Research Article

Automatic inference model construction for computer-aided diagnosis of lung nodule: Explanation adequacy, inference accuracy, and experts’ knowledge

Masami Kawagishi,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Canon Inc., Ohta-ku, Tokyo, Japan
⨯
Takeshi Kubo,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan
⨯
Ryo Sakamoto,

Roles Data curation, Investigation, Writing – review & editing

Affiliations Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan, Preemptive Medicine and Lifestyle-related Disease Research Center, Kyoto University Hospital, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan
⨯
Masahiro Yakami,

Roles Data curation, Investigation, Project administration, Writing – review & editing

Affiliations Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan, Preemptive Medicine and Lifestyle-related Disease Research Center, Kyoto University Hospital, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan
⨯
Koji Fujimoto,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Human Brain Research Center, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan
⨯
Gakuto Aoyama,

Roles Data curation, Resources, Software, Writing – review & editing

Affiliation Canon Inc., Ohta-ku, Tokyo, Japan
⨯
Yutaka Emoto,

Roles Data curation, Investigation, Writing – review & editing

Affiliation Department of Medical Science, Kyoto College of Medical Science, Imakita, Oyama-Higashimachi, Sonobe-cho, Nantan, Kyoto, Japan
⨯
Hiroyuki Sekiguchi,

Roles Investigation, Software, Writing – review & editing

Affiliation Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan
⨯
Koji Sakai,

Roles Investigation, Writing – review & editing

Affiliation Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Kyoto, Japan
⨯
Yoshio Iizuka,

Roles Resources, Software, Writing – review & editing

Affiliation Canon Inc., Ohta-ku, Tokyo, Japan
⨯
Mizuho Nishio ,

Roles Writing – review & editing

* E-mail: nmizuho@kuhp.kyoto-u.ac.jp, jurader@yahoo.co.jp

Affiliations Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan, Preemptive Medicine and Lifestyle-related Disease Research Center, Kyoto University Hospital, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan

http://orcid.org/0000-0002-6037-2338

⨯
Hiroyuki Yamamoto,

Roles Project administration, Supervision, Writing – review & editing

Affiliation Canon Inc., Ohta-ku, Tokyo, Japan
⨯
Kaori Togashi

Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Shogoin, Sakyo-ku, Kyoto, Kyoto, Japan
⨯

Automatic inference model construction for computer-aided diagnosis of lung nodule: Explanation adequacy, inference accuracy, and experts’ knowledge

Masami Kawagishi,
Takeshi Kubo,
Ryo Sakamoto,
Masahiro Yakami,
Koji Fujimoto,
Gakuto Aoyama,
Yutaka Emoto,
Hiroyuki Sekiguchi,
Koji Sakai,
Yoshio Iizuka

Published: November 16, 2018
https://doi.org/10.1371/journal.pone.0207661

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