Substrate-independent immunomodulatory characteristics of mesenchymal stem cells in three-dimensional culture

Jing Li; Tong Chen; Xiahe Huang; Yunshan Zhao; Bin Wang; Yanyun Yin; Yi Cui; Yannan Zhao; Ruiping Zhang; Xiujie Wang; Yingchun Wang; Jianwu Dai

doi:10.1371/journal.pone.0206811

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Open Access

Peer-reviewed

Research Article

Substrate-independent immunomodulatory characteristics of mesenchymal stem cells in three-dimensional culture

Jing Li,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliations Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing, China, State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

http://orcid.org/0000-0002-8914-4005

⨯
Tong Chen,

Roles Data curation, Formal analysis

Affiliations University of Chinese Academy of Sciences, Beijing, China, The State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Xiahe Huang,

Roles Data curation, Formal analysis

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Yunshan Zhao,

Roles Writing – review & editing

Affiliation Institute of General Surgery, Chinese PLA General Hospital, Beijing, China
⨯
Bin Wang,

Roles Writing – original draft

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Yanyun Yin,

Roles Resources

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Yi Cui,

Roles Resources

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Yannan Zhao,

Roles Resources

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Ruiping Zhang,

Roles Resources

Affiliation Department of Radiology, First Clinical Medical School of Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Xiujie Wang,

Roles Data curation, Formal analysis

Affiliation The State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Yingchun Wang,

Roles Data curation, Formal analysis

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯
Jianwu Dai

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: jwdai@genetics.ac.cn

Affiliation State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
⨯

Substrate-independent immunomodulatory characteristics of mesenchymal stem cells in three-dimensional culture

Jing Li,
Tong Chen,
Xiahe Huang,
Yunshan Zhao,
Bin Wang,
Yanyun Yin,
Yi Cui,
Yannan Zhao,
Ruiping Zhang,
Xiujie Wang

Published: November 8, 2018
https://doi.org/10.1371/journal.pone.0206811

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T cells
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Gene expression
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