Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Samuel S. Linton; Thomas Abraham; Jason Liao; Gary A. Clawson; Peter J. Butler; Todd Fox; Mark Kester; Gail L. Matters

doi:10.1371/journal.pone.0206759

Loading metrics

Open Access

Peer-reviewed

Research Article

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Samuel S. Linton,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Current address: The Rockefeller University, New York, New York, United States of America

Affiliation Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Thomas Abraham,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Neural and Behavioral Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Jason Liao,

Roles Formal analysis

Affiliation Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Gary A. Clawson,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Department of Pathology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Peter J. Butler,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Department of Engineering, Pennsylvania State University, University Park, Pennsylvania, United States of America
⨯
Todd Fox,

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Pharmacology, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Mark Kester,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Pharmacology, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Gail L. Matters

Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: gmatters@pennstatehealth.psu.edu

Affiliation Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

http://orcid.org/0000-0001-8613-8649

⨯

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Samuel S. Linton,
Thomas Abraham,
Jason Liao,
Gary A. Clawson,
Peter J. Butler,
Todd Fox,
Mark Kester,
Gail L. Matters

Published: November 1, 2018
https://doi.org/10.1371/journal.pone.0206759

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Exosomes
Is the Subject Area "Exosomes" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Pancreatic cancer
Is the Subject Area "Pancreatic cancer" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Secretion
Is the Subject Area "Secretion" applicable to this article?

Thanks for your feedback.
Metastasis
Is the Subject Area "Metastasis" applicable to this article?

Thanks for your feedback.
Monocytes
Is the Subject Area "Monocytes" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.