The deletion of the ORF1 and ORF71 genes reduces virulence of the neuropathogenic EHV-1 strain Ab4 without compromising host immunity in horses

• Christine L. Wimer ,

  Contributed equally to this work with: Christine L. Wimer, Christiane L. Schnabel

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Christiane L. Schnabel ,

  Contributed equally to this work with: Christine L. Wimer, Christiane L. Schnabel

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

  http://orcid.org/0000-0003-1561-8877

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• Gillian Perkins,

  Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Susanna Babasyan,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Heather Freer,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Alison E. Stout,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Alicia Rollins,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Nikolaus Osterrieder,

  Roles Resources, Writing – review & editing

  Affiliation Institut für Virologie, Freie Universität Berlin, Berlin, Germany

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• Laura B. Goodman,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Amy Glaser,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Bettina Wagner

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bw73@cornell.edu

  Affiliation Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

  http://orcid.org/0000-0003-2370-6324

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