Suppression of miR-22, a tumor suppressor in cervical cancer, by human papillomavirus 16 E6 via a p53/miR-22/HDAC6 pathway

Weerayut Wongjampa; Tipaya Ekalaksananan; Peechanika Chopjitt; Jureeporn Chuerduangphui; Pilaiwan Kleebkaow; Natcha Patarapadungkit; Chamsai Pientong

doi:10.1371/journal.pone.0206644

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Open Access

Peer-reviewed

Research Article

Suppression of miR-22, a tumor suppressor in cervical cancer, by human papillomavirus 16 E6 via a p53/miR-22/HDAC6 pathway

Weerayut Wongjampa,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand
⨯
Tipaya Ekalaksananan,

Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliations Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand
⨯
Peechanika Chopjitt,

Roles Data curation

Affiliations HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand, Faculty of Public Health, Kasetsart University Chalermphrakiat, Sakon Nakhon Campus, Sakon Nakhon, Thailand
⨯
Jureeporn Chuerduangphui,

Roles Data curation

Affiliations Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand
⨯
Pilaiwan Kleebkaow,

Roles Resources

Affiliations HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand, Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
⨯
Natcha Patarapadungkit,

Roles Resources

Affiliations HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
⨯
Chamsai Pientong

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

* E-mail: chapie@kku.ac.th

Affiliations Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, HPV & EBV and Carcinogenesis Research Group, Khon Kaen University, Khon Kaen, Thailand

http://orcid.org/0000-0003-2797-043X

⨯

Suppression of miR-22, a tumor suppressor in cervical cancer, by human papillomavirus 16 E6 via a p53/miR-22/HDAC6 pathway

Weerayut Wongjampa,
Tipaya Ekalaksananan,
Peechanika Chopjitt,
Jureeporn Chuerduangphui,
Pilaiwan Kleebkaow,
Natcha Patarapadungkit,
Chamsai Pientong

Published: October 31, 2018
https://doi.org/10.1371/journal.pone.0206644

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Cervical cancer
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MicroRNAs
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Transfection
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Breast cancer
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Apoptosis
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HPV-16
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Prostate cancer
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Gene expression
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