MR-based spatial normalization improves [¹⁸F]MNI-659 PET regional quantification and detectability of disease effect in the Q175 mouse model of Huntington’s disease

• Daniele Bertoglio,

  Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium

  http://orcid.org/0000-0003-4205-5432

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• Jeroen Verhaeghe,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium

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• Lauren Kosten,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium

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• David Thomae,

  Roles Data curation, Formal analysis, Investigation

  Affiliations Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium, Department of Nuclear Medicine, Antwerp University Hospital, Edegem, Belgium

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• Annemie Van der Linden,

  Roles Resources, Supervision

  Affiliation Bio-Imaging Lab, University of Antwerp, Wilrijk, Belgium

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• Sigrid Stroobants,

  Roles Resources, Supervision

  Affiliations Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium, Department of Nuclear Medicine, Antwerp University Hospital, Edegem, Belgium

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• John Wityak,

  Roles Conceptualization, Resources, Supervision

  Affiliation CHDI Foundation, Princeton, NJ, United States of America

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• Celia Dominguez,

  Roles Resources, Supervision

  Affiliation CHDI Foundation, Princeton, NJ, United States of America

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• Ladislav Mrzljak,

  Roles Conceptualization, Methodology, Resources, Supervision

  Affiliation CHDI Foundation, Princeton, NJ, United States of America

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• Steven Staelens

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: steven.staelens@uantwerpen.be

  Affiliation Molecular Imaging Center Antwerp (MICA), University of Antwerp, Wilrijk, Belgium

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